Hi! I’m Srilakshmi Ranjith, a cell biologist from India,  with a deep love for understanding how life is sustained and how it works at the most fundamental level.  I completed my Integrated Master’s at the Indian Institute of Science Education and Research (IISER), where I explored how proteins like STIL and SAS6 regulate microtubule nucleation and centriole biogenesis, using siRNA knockdowns and expansion microscopy.

Outside the lab, I’m passionate about science communication—especially making complex ideas accessible through storytelling. I also enjoy cooking and getting lost in a good crime thriller.

As an MSCA Doctoral candidate, I’m excited to dive into the world of cilia biology, collaborate across borders and disciplines, and contribute to a vibrant scientific community, both in research and in public dialogue.

Investigation of vesicle trafficking to the primary using advanced microscopy and AI-based image analysis

DC11 will investigate microtubule-based pathways responsible for the formation of the primary cilium of kidney epithelial cells and other cells. This will be done by (1) Using recently developed in vitro reconstitution assays and AI-based image analysis to study the biochemical activities of molecular players involved in ciliary axoneme formation; (2) Mapping the three-dimensional organization of the microtubule network and ciliary formation intermediates using Expansion Microscopy and perform data analysis using AI-based technologies; (3) Using 3D live imaging with Lattice Light Sheet and Spinning Disk microscopy combined with AI-based analysis to determine the transport and trafficking pathways of (membrane) proteins to the cilium.